The Colloid Crystalloid Question • Is one of the oldest. • Basic yet fundamental question. • The first intervention given. • To every patient. • Often several litres. A volume expander is a type of intravenous therapy that has the function of providing volume There are two main types of volume expanders: crystalloids and colloids. Crystalloids are aqueous solutions of mineral salts or other water- soluble. Colloids and crystalloids are types of fluids that are used for fluid replacement, often intravenously (via a tube straight into the blood).

Author: Kigacage Zulull
Country: Sri Lanka
Language: English (Spanish)
Genre: Relationship
Published (Last): 24 May 2016
Pages: 58
PDF File Size: 15.72 Mb
ePub File Size: 4.85 Mb
ISBN: 726-5-94258-404-6
Downloads: 58981
Price: Free* [*Free Regsitration Required]
Uploader: Zule

Colloids can be man-made e. Colloids have larger molecules, colloici more, and may provide swifter volume expansion in the intravascular space, but may induce allergic reactions, blood clotting disorders, and kidney failure.

Using albumin or FFP compared to crystalloids may make little or no difference to the need for renal replacement therapy. Using starches, dextrans, albumin or FFP moderate-certainty evidenceor gelatins low-certainty evidenceversus crystalloids probably makes little or no difference to mortality.

NS is used frequently in intravenous drips IVs for patients who cannot take fluids orally and have developed or are in danger of developing dehydration or hypovolemia.

From Wikipedia, the free encyclopedia.

Crystalloid vs colloid rx

Its use in those who are very ill is associated with an increased risk of death and kidney problems and thus is not recommended in people with known inflammatory conditions such as renal impairment.

Retrieved 31 August NS is typically the first fluid used when hypovolemia is severe enough to threaten the adequacy of blood circulation, and has long been believed to be the safest fluid to give quickly in large volumes.


We searched the medical literature and identified 69 relevant studies with 30, critically ill participants who were given fluid replacement in hospital or in an emergency out-of-hospital setting. This page was last edited on 4 Novemberat No studies measured RRT. However in some circumstances, hyperbaric oxygen therapy ceistalloidi maintain adequate tissue oxygenation even if red blood cell levels are below normal life-sustaining levels.

We found moderate-certainty evidence that starches probably slightly increase the need for blood transfusion RR 1. Using albumin or FFP may make little or no difference to the need for renal replacement therapy.

It is an intravenous colloid that behaves much like blood filled with albumins. We are uncertain whether they are better than crystalloids at reducing death, need for blood transfusion or need for renal replacement therapy filtering the blood, with or without dialysis machines, if kidneys fail when given to critically ill people who need fluid replacement.

Fourteen studies included participants in the crystalloid group who received or may have received colloids, which might have influenced results. Similarly, we are uncertain if colloids or crystalloids increase the number of adverse events.

The Cochrane Database of Systematic Reviews. All articles with dead external links Articles with dead external links from May Wikipedia articles in need of updating from November All Wikipedia articles in need of updating. Are particular types of colloid solution safer for replacing blood fluids than others? Otherwise, the choice to use crystalloid versus colloid should be based upon the comorbidities of the patient and the overall clinical picture.

Colloids contain larger insoluble molecules, such as gelatin ; blood itself is a colloid. Theoretical advantages of using hydroxyethyl starch HES for goal-directed therapy include a reduction in the total volume of fluid required, resulting in less tissue oedema.


Ten studies were in out-of-hospital settings. It may make little or no difference to the number of people who die if gelatins or crystalloids are used for fluid replacement. Critically ill people may lose large amounts of blood because of trauma or burnsor have serious conditions or infections e.

Also, we found that some people who were given crystalloids may also have had colloids, which might have affected the results. Starches probably slightly increase the need for blood transfusion and RRT moderate-certainty evidenceand criztalloidi or FFP may make little or no difference to the need for renal replacement therapy low-certainty evidence.

By using this site, you agree to the Terms of Use and Privacy Policy.

We found little or no difference in allergic reactions for the use of dextrans four studiesgelatins one studyand albumin or FFP one study. Retrieved from ” https: We found moderate-certainty evidence that there is probably little or no difference between cristaloidi albumin or FFP or using crystalloids in mortality at: This way remaining red blood cells can still oxygenate body tissue.

Crystalloid or colloid: does it matter?

Blood substitutes Intravenous fluids. Few studies reported adverse events specifically, allergic reactions, itching, or rashesso we are uncertain whether either cristtalloidi type causes fewer adverse events very low-certainty evidence. We excluded neonates, elective surgery and caesarean section. You may also be interested in: Independently, two review authors assessed studies for inclusion, extracted dataassessed risk of biasand synthesised findings.